Risk of heart diseases in young and teenager increases with exposure to diabetes in womb finds a recent study. The research was published online in CMAJ (Canadian Medical Association Journal).
Researchers at Manitoba, Canada, analyzed the data of 290 000 people since their birth to 35 years of age, the study revealed that exposure to maternal diabetes during pregnancy was associated with higher morbidity and risk to cardiovascular disease among offspring up to 35 years of age.
There is few other research that found that Postmenopausal women with more belly fat are at increased risk of heart disease and even on of the study has found that Blood pressure, cholesterol in young adult linked to risk of heart attack later.
In this article, we will learn more about this recent in which heart disease in teenagers and young people is linked to mother suffering from diabetes during pregnancy.
Maternal diabetes and heart disease
Scientists already knew that maternal undernutrition is associated with higher rates of premature cardiovascular diseases. However, they were curious about its association with maternal diabetes in young and teenagers.
To find out this, researchers at Manitoba, Canada performed cohort study on more than 290 000 children born between 1979 and 2005 and followed until March 2015. These all children were exposed to maternal diabetes and type 2 diabetes mellitus.
In their study, doctors were primarily looking for incident cardiovascular disease events, and the secondary outcome was a composite of risk factors for cardiovascular disease in offspring followed up to age 35 years.
Result was something to concern
Out of 3 628 576 person-years of data; 2765 (0.9%) of the offspring experienced a cardiovascular disease endpoint, and 12 673 (4.3%) experienced a cardiovascular disease risk factor. Researchers also found the hazard for cardiovascular disease end points was elevated in offspring exposed to gestational diabetes but not type 2 diabetes. A similar association was observed for cardiovascular disease risk factors.
This clearly indicated that intrauterine exposure to maternal diabetes was associated with higher morbidity and risk related to cardiovascular disease among offspring up to 35 years of age.
Keep Reading: Heart failure & Diabetes: High risk of heart failure in diabetic women than men
Journal reference:
Intrauterine exposure to diabetes and risk of cardiovascular disease in adolescence and early adulthood: a population-based birth cohort studyLaetitia Guillemette, Brandy Wicklow, Elizabeth A.C. Sellers, Allison Dart, Garry X. Shen, Vernon W. Dolinsky, Joseph W. Gordon, Davinder S. Jassal, Nathan Nickel, Todd A. Duhamel, Dan Chateau, Heather J. Prior, Jonathan McGavockCMAJ Sep 2020, 192 (39) E1104-E1113; DOI: 10.1503/cmaj.190797
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