Osteoporosis: Womens at more risk for chemicals in toothpaste

Last updated on June 12th, 2020 at 11:19 am

Women who are exposed to triclosan (TCS), a commonly used chemical antibacterial in soaps, toothpaste and other personal care products, are at increased chances of developing osteoporosis, a study has found.

A research published on 25 June 2019 in the Journal of Clinical Endocrinology & Metabolism is the first epidemiological study to investigate the association between urinary TCS concentration with BMD (Bone Mass Density) and osteoporosis in the US adult women.

Research found that women with more urinary TCS concentration has reduced BMD and has more prevalence of osteoporosis.

Research methodology

The researchers in the US used 2005-2010 National Health and Nutrition Examination Survey data to examine the association between urinary TCS concentrations with BMD and osteoporosis. They analyzed 1,848 adult women of age 20 years or more.

Scientist already knew that Triclosan (TCS) could result in significant interstitial collagen accumulation and an increase in trabecular bone. However, little is known about the relationship between TCS exposure and human bone health.

Result

Scientist observed significant associations between tertile TCS concentration and lower BMD in regions of the total femur and lumbar spine.

It clearly states proves TCS concentration was negatively associated with BMD and was positively associated with the prevalence of osteoporosis.

The evidence was stronger in postmenopausal women than in premenopausal women. Future prospective studies are needed to validate the findings.

Resource

1. Association between urinary triclosan with bone mass density and osteoporosis in the US adult women, 2005-2010/ Research pubslishe 25 June 2019: https://academic.oup.com/jcem/advance-article-abstract/doi/10.1210/jc.2019-00576/5522022