Nitrate Supplement can Improve Breathing in Seniors|Study

Nitrate Supplement can Improve Breathing in Seniors

New research has revealed that intake of sufficient dietary nitrate supplementation can improve the function of the diaphragm, thereby improving breathing and coughing. This research is essential for elderly people suffering from breathing problems. This US-based study was published in The Journal of Physiology. The research on mice reveals that dietary nitrate supplementation increases diaphragm peak power in old mice1.

What is the diaphragm, how does its improved function affect breathing, and what are the sources of dietary nitrate? Let’s try to answer all these questions in this article.

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Nitrate supplement and improved breathing

The research team at the University of Florida conducted a study on mice and found that dietary nitrate supplementation elicited a pronounced increase in the diaphragm’s contractile function (power).

nitrate supplementation increases diaphragm contraction power improves breathing

If you are unaware of the diaphragm, it is a vital respiration organ at the base of our thoracic cage. When we inspire, the diaphragm descends to create a vacuum inside the rib cage, and air rushes inside through the nose or mouth. The exact opposite happens when we expire; the diaphragm ascends to push impure air out of the lungs.

However, the function of the diaphragm declines with age, contributing to ventilatory dysfunction, impaired airway clearance, and overall decreased quality of life. Diaphragm isotonic and isometric contractile properties are reduced with ageing, including maximal specific force, shortening velocity and peak power.

Scientists already knew the effect of dietary supplements on the contractile properties of limb muscles in both humans and rodents. However, they were curious about its beneficial effect on respiratory muscles.

But what made researchers conclude that it can also benefit the respiratory muscles?

Research Overview

Researchers hypothesized that dietary nitrate supplementation would improve diaphragm contractile properties in aged mice. To test this hypothesis, scientists performed tests on mice.

They allocated 1 mm of NaNO3 in the drinking water of old (24 months) mice for the next 14 days. After 14 days, they measured the diaphragm function of those mice.

Result

The maximal rate of isometric force development and peak power (40%) increased with nitrate supplementation. In general, the study demonstrates improved diaphragm contractile function with dietary nitrate supplementation and supports using this strategy to enhance inspiratory function in ageing populations.

Dietary sources of nitrate

beet, source of nitrate

Approximately 80% of dietary nitrates are derived from vegetable consumption; sources of nitrites include vegetables, fruit, and processed meats. These are the rich sources of nitric oxide:

  1. Beets
  2. Pomegranate
  3. Watermelon
  4. Garlic
  5. Citrus fruit
  6. Dark chocolate

Other benefits of dietary nitrates


  • In the body, nitrates can turn into nitric oxide (NO) that causes blood vessels to dilate and reduces blood pressure.
  • Studies suggest dietary nitrates and nitrites enhance physical performance, especially during high-intensity endurance exercise.

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Dr Sunit Sanjay Ekka is a physiotherapist in practice for the last 15 years. He has done his BPT from one of the premium Central Government physiotherapy colleges, ie, SVNIRTAR. The patient is his best teacher and whatever he gets to learn he loves to share it on his Youtube channel and blog.



Reference
1↑ Kumar RA, Kelley RC, Hahn D, Ferreira LF. Dietary nitrate supplementation increases diaphragm peak power in old mice. J Physiol. 2020 Oct;598(19):4357-4369. doi: 10.1113/JP280027. Epub 2020 Aug 16. PMID: 33460123; PMCID: PMC10195135. Visit

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